Bibi Amro was the daughter of Guru Angad, the second Nanak. She was born in 1532 in the village of Khadur Sahib, in present-day district of Amritsar. She received her early education and training directly from her parents, Guru Angad and Mata Khivi. Guru Angad spent a lot of time with his children. He taught them the Gurmukhi script that he had refined and which has been used in Guru Granth Sahib. When she came of age she was married to Bhai Jasoo, son of Manak Chand of Basarke village.

As per the custom, she was sent to live with her husband's family. Her father encouraged her to continue doing kirtan and to preach Sikhism to all that she came in contact with. Baba Amar Das, who was her husband's uncle, was quite taken by her sweet melodious voice when he heard her singing shabads (holy hymns). It was she who first introduced him to the teachings of Sikhism. As his interest grew it was she who sent him to her father to learn more about these teachings. Amar Das was so deeply influenced by Guru Angad that he became such a devout Sikhs that Guru Angad announced him as his successor. Thus, Guru Amar Das, the third Nanak, got to his destiny of becoming a Guru through Bibi Amro.

Years later when Guru Amar Das gave organisational structure to the Sikh Nation and organised his preachers into 22 teaching districts he put Bibi Amro ji in-charge of one of these districts that he callcd Manji. What Manji meant was that a person who was leading the Kirtan would sit on the Manji while whole sangat sat in front of him.

The person occupying Manji was the Sikh preacher appointed by Guru Amardas. This appointment can best be compared to the position of Bishop in the Christian Church today. It was an administrative position, with full responsibility for the equality and content of the preaching. She also would have the responsibility of collecting revenues and making decisions for the welfare of the sangat. Her Manji included Basarke, her husband's village, where they made their home. It is the direct result of the efforts of Bibi Amro and other Sikh preachers that Amritsar today is synonymous with Sikhism. Today, close to the village of Basarke, there is a tank (man-made pond) bearing the name Bibi Amro da Talab (Tank of Bibi Amro) in her memory.